Spindle Positioning, Meiotic Nonreduction, and Polyploidy in Plants

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Spindle Positioning, Meiotic Nonreduction, and Polyploidy in Plants

Polyploidy, the state of having more than two sets of chromosomes, is common in flowering plants (angiosperms), including the major crops [1]. Indeed, it is estimated that 30%–80% of the angiosperms are polyploids [2], and most diploid plant species, including Arabidopsis thaliana, show evidence of genome duplication in their ancestry [3]. Polyploidy is accompanied by genome-wide changes in gen...

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Meiotic spindle, spindle checkpoint and embryonic aneuploidy.

In mitosis, a spindle checkpoint plays important roles at the metaphase-anaphase transition to ensure the formation of a bipolar spindle, the completion of connecting chromosomes to microtubules and the alignment of all chromosomes at the spindle equator before initiation of anaphase. Components of the spindle checkpoint were first identified through genetic screens in budding yeast and some ch...

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Revisiting ancestral polyploidy in plants

Whole-genome duplications (WGDs) or polyploidy events have been studied extensively in plants. In a now widely cited paper, Jiao et al. presented evidence for two ancient, ancestral plant WGDs predating the origin of flowering and seed plants, respectively. This finding was based primarily on a bimodal age distribution of gene duplication events obtained from molecular dating of almost 800 phyl...

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Polyploidy and genome evolution in plants.

Genome doubling (polyploidy) has been and continues to be a pervasive force in plant evolution. Modern plant genomes harbor evidence of multiple rounds of past polyploidization events, often followed by massive silencing and elimination of duplicated genes. Recent studies have refined our inferences of the number and timing of polyploidy events and the impact of these events on genome structure...

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Meiotic Spindle Structure

Meiotic chromosome segregation leads to the production of haploid germ cells. During meiosis I (MI) the paired homologous chromosomes are separated. Meiosis II (MII) segregation leads to the separation of paired sister chromatids. In the budding yeast, Saccharomyces cerevisiae, both of these divisions take place in a single nucleus, giving rise to the four spored ascus. We have modeled the micr...

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ژورنال

عنوان ژورنال: PLoS Genetics

سال: 2008

ISSN: 1553-7404

DOI: 10.1371/journal.pgen.1000272